Measurement of blood glucose levels.

• Screening for type 1/2 diabetes
• Detection of hypoglycemia
• Monitoring glycemic balance

Venous blood (fluoride tube)

Fasting 8-12h for fasting glucose, 2h after a meal for postprandial.

• Routine health check-up
• Pregnancy monitoring
• Antidiabetic treatment monitoring

0.70-1.10 g/L fasting

HbA1c • HGPO • Insulinémie • Fructosamine

Dynamic test measuring blood glucose after ingestion of 75g of glucose.

• Diagnosis of gestational diabetes
• Confirmation of pre-diabetes
• Assessment of insulin resistance

Venous blood (T0, T60, T120)

Fasting 10-12h, normal diet 3 days before, rest during the test.

• Screening at 24th-28th week of pregnancy
• Borderline fasting glucose

Glycémie • Insulinémie • HbA1c

Measurement of glycated hemoglobin, reflecting the average blood glucose over the past 2-3 months.

• Monitoring glycemic balance
• Assessment of treatment efficacy
• Diabetes diagnosis (≥6.5%)

Venous blood (EDTA tube)

No preparation required (no fasting needed).

• Quarterly check-up for diabetic patients
• Treatment adjustment
• Diabetes screening

< 5.7% normal; 5.7-6.4% pre-diabetes; ≥ 6.5% diabetes

Glycémie • Fructosamine • Peptide C

Measurement of glycated plasma proteins, reflecting glycemic balance over the past 2-3 weeks.

• Short-term glycemic monitoring
• Alternative to HbA1c in cases of hemoglobinopathy
• Rapid assessment after treatment modification

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Gestational diabetes monitoring
• Patients with hemoglobin abnormalities
• Assessment of therapeutic change

Glycémie • HbA1c • Insulinémie

Protein fragment released with insulin by the beta cells of the pancreas.

• Distinction between type 1/2 diabetes
• Assessment of residual beta cell function
• Insulinoma diagnosis

Venous blood (dry tube)

Fasting 8-12h recommended.

• Diabetes type classification
• Post-transplant pancreatic function monitoring
• Investigation of unexplained hypoglycemia

Insulinémie • Glycémie • HbA1c

Measurement of circulating insulin levels.

• Diagnosis of insulin resistance / metabolic syndrome
• Investigation of hypoglycemia (insulinoma)
• Assessment of pancreatic function

Venous blood (dry tube)

Fasting 10-12h, possible discontinuation of insulin therapy per medical advice.

• Obesity or PCOS workup
• Investigation of reactive hypoglycemia
• HOMA index calculation

Glycémie • Peptide C • HbA1c • HGPO

End product of protein catabolism.

• Assessment of kidney function
• Detection of renal insufficiency
• Assessment of hydration and protein intake

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Routine kidney workup
• Renal insufficiency monitoring
• Dehydration assessment

Créatinine • Ionogramme • Acide urique

Metabolic waste product of muscle creatine, marker of glomerular filtration rate (GFR).

• Assessment of glomerular function
• GFR calculation (CKD-EPI / MDRD)
• Monitoring of nephrotoxic treatments

Venous blood (24h urine collection possible)

No strict fasting required, avoid intense exercise the day before.

• Annual health check-up
• Chronic kidney disease monitoring
• Dosage adjustment

Urée • Ionogramme • Acide urique • Albuminémie

End product of purine metabolism.

• Diagnosis and monitoring of gout
• Assessment of uric acid stone risk
• Chemotherapy monitoring (tumor lysis)

Venous blood (dry tube)

Fasting 8h, avoid red meat, organ meats and alcohol before sampling.

• Investigation of acute arthritis
• Metabolic workup
• Hyperuricemia monitoring

Créatinine • Urée • Ionogramme

Measurement of the main blood electrolytes.

• Assessment of fluid and electrolyte balance
• Detection of hypo/hyperkalemia
• Monitoring under diuretic therapy

Venous blood (without prolonged tourniquet)

Report any ongoing diuretic treatment.

• Preoperative workup
• Renal/cardiac insufficiency monitoring
• Monitoring under diuretics/ACE inhibitors/ARBs
• Investigation of consciousness disorders/cramps

Urée • Créatinine • Calcémie • Magnésémie

Measurement of blood calcium, phosphorus and magnesium levels.

• Investigation of phosphocalcic metabolism
• Diagnosis of hyper/hypocalcemia
• Assessment of bone disorders
• Detection of hypomagnesemia

Venous blood (dry tube)

Fasting 8h recommended for phosphorus.

• Osteoporosis workup
• Investigation of cramps/tetany
• Vitamin D/calcium supplementation monitoring
• Thyroid/parathyroid preoperative workup

PTH • Vitamine D • Phosphatases alcalines • Ionogramme

Yellow pigment resulting from hemoglobin degradation.

• Etiological diagnosis of jaundice
• Distinction between hemolytic/hepatocellular/obstructive jaundice
• Assessment of liver function

Venous blood (light-protected tube)

Fasting recommended, avoid hemolysis during sampling.

• Investigation of neonatal jaundice
• Hepatitis/cirrhosis workup
• Cholestasis investigation

TGO/TGP • PAL • GGT • Albuminémie

Measurement of liver transaminases.

• Detection and monitoring of liver damage
• Assessment of drug-induced hepatotoxicity
• Differential diagnosis of hepatic/muscular damage

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Routine liver workup
• Chronic viral hepatitis monitoring
• Hepatotoxic treatment monitoring

GGT • PAL • Bilirubine • Albuminémie • LDH

Enzymes found in the liver, bones, intestines and placenta.

• Diagnosis of cholestasis
• Detection of bone pathologies
• Monitoring bone growth in children

Venous blood (dry tube)

Fasting recommended (ALP increases after a fatty meal).

• Investigation of obstructive jaundice
• Bone pain workup
• Cancer with bone metastases monitoring

GGT • Bilirubine • TGO/TGP • Calcémie

Liver enzyme sensitive to cholestasis and alcohol consumption.

• Screening for excessive alcohol consumption
• Diagnosis of cholestasis
• Hepatotoxicity monitoring

Venous blood (dry tube)

Fasting 8h, report any ongoing treatment.

• Standard liver workup
• Alcohol withdrawal monitoring
• Investigation of isolated ALP elevation

PAL • Bilirubine • TGO/TGP

Pancreatic enzyme, reference marker for acute pancreatitis.

• Diagnosis of acute pancreatitis
• Assessment of pancreatic damage severity
• Distinction between pancreatic/non-pancreatic pain

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Acute epigastric abdominal pain
• Suspected alcoholic/biliary pancreatitis
• Chronic pancreatitis monitoring

Amylase • Bilirubine • TGO/TGP • Triglycérides

Enzyme produced by the pancreas and salivary glands.

• Complementary diagnosis of acute pancreatitis
• Detection of salivary gland pathology
• Assessment of effusion

Venous blood (or urine)

No specific preparation required. Preferably come in the morning.

• Complement to lipase in emergency
• Investigation of abdominal pain
• Parotitis diagnosis

Lipase • Bilirubine • Calcémie

The most abundant protein in blood plasma.

• Assessment of hepatic synthesis function
• Nutritional status assessment
• Detection of protein loss

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Malnutrition workup
• Cirrhosis monitoring
• Edema investigation
• Corrected calcium interpretation

Électrophorèse des protéines • Bilirubine • Créatinine • TGO/TGP

Protein specific to the myocardium.

• Diagnosis of myocardial infarction
• Assessment of myocardial distress
• Cardiovascular risk stratification

Venous blood (emergency results)

No preparation required (emergency context).

• Acute chest pain in emergency department
• Suspected myocardial infarction
• Post-angioplasty/cardiac surgery follow-up
• Myocarditis diagnosis

CPK/CK-MB • NT-ProBNP • D-dimères • LDH

Fragment of B-type natriuretic peptide.

• Diagnosis of heart failure
• Distinction between cardiac/pulmonary dyspnea
• Heart failure treatment monitoring

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Acute dyspnea in emergency department
• Heart failure patient monitoring
• Preoperative cardiac risk assessment

Troponine • CPK • Ionogramme • Créatinine

Total creatine phosphokinase and cardiac MB fraction.

• Diagnosis of myocardial infarction (CK-MB)
• Detection of rhabdomyolysis
• Monitoring of myopathies and statins

Venous blood (dry tube)

Avoid intense exercise 48h before sampling.

• Chest pain (complement to troponin)
• Muscle pain under statins
• Investigation of muscle weakness

Troponine • LDH • NT-ProBNP • TGO

Fibrin degradation products.

• Exclusion of deep vein thrombosis (DVT)
• Exclusion of pulmonary embolism
• Aid in DIC diagnosis

Venous blood (citrate tube)

No specific preparation required. Preferably come in the morning.

• Suspected phlebitis/pulmonary embolism
• Diagnostic algorithm (Wells, Geneva)
• DIC monitoring

< 500 µg/L (age-adjusted: age × 10 µg/L after 50 years)

TP • TCA • Fibrinogène • Troponine

Ubiquitous intracellular enzyme.

• Marker of cell lysis
• Tumor monitoring (lymphomas, germ cell tumors)
• Assessment of hemolytic anemia severity

Venous blood (avoid hemolysis)

No specific preparation required. Preferably come in the morning.

• Investigation of hemolytic anemia
• Lymphoma treatment monitoring
• Prognostic marker in oncology

Haptoglobine • Bilirubine • Réticulocytes • CPK

Acute phase inflammation protein.

• Detection and monitoring of bacterial infection
• Assessment of chronic inflammatory disease activity
• Distinction between bacterial/viral infection

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Fever of unknown origin
• Postoperative follow-up
• Inflammatory disease monitoring

Procalcitonine • FNS • VS • Fibrinogène

Precursor of calcitonin.

• Diagnosis of sepsis and severe bacterial infections
• Antibiotic therapy guidance
• Distinction between bacterial/viral infection

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Sepsis / septic shock
• Lower respiratory tract infection
• Antibiotic stewardship

CRP • FNS • Hémocultures • Lactates

Anti-streptolysin O antibodies.

• Serological evidence of streptococcal infection
• Aid in diagnosis of rheumatic fever
• Investigation of post-streptococcal glomerulonephritis

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Recurrent tonsillitis with complications
• Post-infectious arthralgia/carditis
• Post-tonsillitis proteinuria/hematuria

CRP • VS • Facteurs rhumatoïdes • Créatinine

Rapid test for infectious mononucleosis (EBV).

• Rapid diagnosis of mononucleosis
• Investigation of mononucleosis-like syndrome

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Prolonged fatigue in adolescents/young adults
• Antibiotic-resistant tonsillitis with lymphadenopathy
• Febrile splenomegaly

FNS • Bilan hépatique • Sérologie EBV

Serological panel for viral hepatitis A, B and C.

• Hepatitis B screening (HBsAg, anti-HBs, anti-HBc)
• Hepatitis C screening (anti-HCV)
• Hepatitis A diagnosis (IgM anti-HAV)
• Hepatitis B vaccination status verification

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Prenuptial/prenatal workup
• Pre-transfusion/preoperative workup
• Chronic hepatitis monitoring
• Vaccine response verification

Bilan hépatique • Charges virales HBV/HCV

Combined HIV screening p24 Ag + anti-HIV 1/2 antibodies (4th generation).

• HIV infection screening
• Early diagnosis (p24 Ag)

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Voluntary/systematic screening
• Prenatal workup
• Blood exposure accident
• STI workup

Sérologie Syphilis • Sérologie Hépatites • FNS

Syphilis screening using TPHA + VDRL tests.

• Syphilis screening
• Treatment efficacy monitoring (VDRL)
• Prenatal screening

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• STI workup
• Prenuptial/prenatal workup
• Genital ulceration
• Post-treatment follow-up

Sérologie VIH • Sérologie Hépatites • PCR IST

Detection of anti-Chlamydia trachomatis antibodies.

• Screening for past/active infection
• Infertility workup

Venous blood (serology) or local swab (PCR)

No specific preparation required. Preferably come in the morning.

• Couple infertility workup
• Screening in young women
• STI workup

PCR IST • Sérologie Syphilis • Prélèvement vaginal

Panel of infections with maternal-fetal risk.

• Determination of maternal immunity (IgG)
• Detection of primary infection during pregnancy (IgM)
• Prevention of congenital infections

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• First trimester prenatal workup
• Monthly toxoplasmosis monitoring in non-immune women
• Febrile syndrome in pregnant women
• Suspected congenital infection

FNS • Bilan hépatique • β-HCG

SARS-CoV-2 screening by antibodies (IgG/IgM) or rapid antigen test.

• Detection of post-infection/vaccination antibodies
• Retrospective diagnosis

Venous blood (serology) or nasopharyngeal swab (antigen test)

No specific preparation required. Preferably come in the morning.

• Post-vaccination immune status verification
• Retrospective diagnosis of past infection
• Epidemiological investigation

CRP • FNS • Procalcitonine

Serological tests for bacterial zoonoses (brucellosis, typhoid fever).

• Brucellosis diagnosis (Wright, Rose Bengal)
• Typhoid fever diagnosis (Widal)
• Screening in endemic areas

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Prolonged fever of unknown origin
• Occupational exposure (farmers, veterinarians)
• Return from travel in endemic area
• Febrile arthritis

Hémocultures • CRP • FNS • Bilan hépatique

Thyroid panel including TSH (thyroid-stimulating hormone), free T3, and free T4. First-line marker for diagnosing thyroid dysfunction.

• Screening and diagnosis of hypothyroidism (elevated TSH)
• Screening and diagnosis of hyperthyroidism (low TSH)
• Monitoring of replacement or suppressive therapy

Venous blood (dry tube)

Morning collection preferred. Patients on levothyroxine should take their medication after the blood draw.

• Fatigue, unexplained weight gain or weight loss
• Cardiac rhythm disorders
• Infertility workup
• Post-thyroidectomy follow-up

Anticorps anti-TPO • Anti-TG • Thyroglobuline

Glycoprotein produced exclusively by thyroid cells. Tumor marker used in post-operative follow-up of differentiated thyroid cancers.

• Follow-up of differentiated thyroid cancers after thyroidectomy
• Detection of recurrence or thyroid metastases

Venous blood (dry tube)

Report any levothyroxine treatment.

• Post-thyroidectomy follow-up for papillary or follicular cancer
• Post-radioiodine therapy surveillance

TSH • Anticorps anti-TG • Échographie thyroïdienne

Measurement of anti-thyroid peroxidase (anti-TPO) and anti-thyroglobulin (anti-TG) autoantibodies. Markers of thyroid autoimmunity.

• Diagnosis of Hashimoto's thyroiditis
• Diagnosis of Graves' disease
• Assessment of autoimmune thyroid dysfunction risk

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Unexplained hypothyroidism
• Diffuse or nodular goiter
• Postpartum thyroiditis
• Thyroglobulin interpretation

TSH • T3L • T4L • Thyroglobuline

Main glucocorticoid hormone produced by the adrenal glands under ACTH control. The assay evaluates adrenocortical function.

• Diagnosis of Cushing's syndrome
• Diagnosis of adrenal insufficiency (Addison's disease)
• Evaluation of cortisol circadian rhythm

Venous blood (serum cortisol, morning at 8am) or 24h urine (free urinary cortisol)

Morning blood collection between 7am and 9am (physiological peak). Rest for 30 minutes before collection.

• Central obesity with purple striae
• Chronic fatigue with hypotension and hyperpigmentation
• Investigation of adrenal incidentaloma

ACTH • Ionogramme • Glycémie

Pituitary hormone (corticotropin) stimulating cortisol secretion by the adrenal glands. Essential for differentiating the origin of hypercortisolism.

• Distinction between central Cushing's (high ACTH) and adrenal Cushing's (low ACTH)
• Diagnosis of secondary adrenal insufficiency

Venous blood (EDTA tube, transported quickly on ice)

Morning collection between 7am and 9am. Rest and fasting required.

• Investigation of hypercortisolism or adrenal insufficiency
• Pituitary adenoma workup

Cortisol • Test au Synacthène • Ionogramme

Measurement of growth hormone (somatotropin) and IGF-1 (Insulin-like Growth Factor 1). GH is secreted in a pulsatile manner; IGF-1 reflects stable somatotropic secretion.

• Diagnosis of growth hormone deficiency in children
• Diagnosis of acromegaly in adults
• Monitoring of growth hormone therapy

Venous blood (dry tube)

Fasting and rest required. Morning collection.

• Growth retardation in children
• Dysmorphic syndrome suggestive of acromegaly
• Surveillance of somatotropic pituitary adenoma

TSH • Cortisol • Prolactine • Glycémie

Measurement of 25-hydroxyvitamin D (25-OH-D), the circulating storage form. Plays a crucial role in calcium absorption, bone mineralization, and immune system modulation.

• Screening and diagnosis of vitamin D deficiency
• Monitoring of supplementation
• Assessment of osteoporosis and rickets risk

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Diffuse bone or muscle pain
• Osteoporosis workup
• Chronic fatigue
• Follow-up of renal insufficiency patients
• At-risk populations (elderly, dark skin, low sun exposure)

30–100 ng/mL (sufficient); 10–30 ng/mL (insufficient); < 10 ng/mL (deficiency)

Calcémie • Phosphorémie • PTH • PAL

Hormone secreted by the parathyroid glands, regulating phosphocalcic metabolism. Acts on bones, kidneys, and intestine to maintain calcium homeostasis.

• Diagnosis of hyperparathyroidism (primary, secondary, tertiary)
• Investigation of hypercalcemia or hypocalcemia
• Monitoring of chronic kidney disease

Venous blood (dry tube)

Fasting recommended. Morning collection.

• Hypercalcemia with recurrent renal lithiasis
• Severe osteoporosis
• Chronic kidney disease follow-up
• Post-thyroidectomy

Calcémie • Phosphorémie • Vitamine D • PAL • Calciurie

Measurement of the beta subunit of human chorionic gonadotropin (β-HCG). Primary biological marker of pregnancy and tumor marker for germ cell tumors.

• Early pregnancy diagnosis
• Approximate pregnancy dating
• Monitoring of high-risk pregnancies
• Tumor marker (germ cell tumors)

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Pregnancy confirmation
• Pelvic pain with suspected ectopic pregnancy
• Post-miscarriage or post-termination follow-up
• First trimester prenatal screening

Échographie pelvienne • Progestérone • FNS

Measurement of anti-Müllerian hormone (AMH), considered the best marker of ovarian reserve. Allows assessment of reproductive potential.

• Evaluation of ovarian reserve
• Prediction of ovarian stimulation response in IVF
• Diagnosis of polycystic ovary syndrome (PCOS)
• In males: evaluation of testicular function

Venous blood (dry tube)

Can be performed at any time during the menstrual cycle.

• Female infertility workup
• Fertility preservation counseling
• Pre-IVF workup
• Suspected PCOS

FSH • LH • Œstradiol • Compte follicules antraux

Measurement of pituitary gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH). Regulate gonadal function in both men and women.

• Investigation of menstrual cycle disorders
• Diagnosis of menopause and premature ovarian insufficiency
• Infertility workup in men and women
• Investigation of delayed or precocious puberty

Venous blood (dry tube)

In women: collection between day 2 and day 5 of the cycle (early follicular phase).

• Primary or secondary amenorrhea
• Menopause workup
• Oligospermia or azoospermia in men
• Delayed puberty

Œstradiol • Progestérone • AMH • Testostérone • Prolactine

Main circulating estrogen, primarily produced by the ovaries. Plays a central role in the development of female sexual characteristics and menstrual cycle regulation.

• Evaluation of ovarian function
• Monitoring of ovarian stimulation in IVF
• Diagnosis of menopause
• Investigation of gynecomastia in men

Venous blood (dry tube)

In women: collection between day 2 and day 5 of the cycle.

• Infertility workup
• Menstrual cycle disorders
• Ovarian stimulation monitoring
• Postmenopausal osteoporosis

FSH • LH • Progestérone • AMH

Steroid hormone produced by the ovarian corpus luteum. Prepares the endometrium for implantation and plays an essential role in maintaining early pregnancy.

• Confirmation of ovulation
• Evaluation of the luteal phase
• Early pregnancy monitoring

Venous blood (dry tube)

Collection during the luteal phase (day 21-23 of the cycle) to confirm ovulation.

• Infertility workup (luteal insufficiency)
• Threatened miscarriage
• Ovarian stimulation monitoring

Œstradiol • FSH • LH • β-HCG

Main androgen produced by the testes in men and in small quantities by the ovaries and adrenal glands in women. Essential role in the development of male sexual characteristics.

• Diagnosis of male hypogonadism
• Investigation of hirsutism and virilization in women
• Evaluation of puberty

Venous blood (dry tube)

Morning collection between 7am and 10am (circadian peak). Fasting recommended.

• Libido disorders and erectile dysfunction
• Female hirsutism
• Male infertility workup
• Androgen therapy monitoring

FSH • LH • SHBG • DHEA • Prolactine

Steroid precursor in the cortisol synthesis pathway. Primary marker for congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

• Screening for congenital adrenal hyperplasia
• Etiological diagnosis of female hyperandrogenism

Venous blood (dry tube)

Morning collection. In women, during the follicular phase (day 2-5 of the cycle).

• Hirsutism with suspected enzymatic block
• Neonatal screening for congenital adrenal hyperplasia
• Hyperandrogenism workup

Cortisol • ACTH • Testostérone • DHEA • Delta 4 androstènedione

Weak androgen precursor of testosterone and estrone. Produced by the ovaries and adrenal glands, useful for investigating the origin of hyperandrogenism.

• Investigation of female hyperandrogenism
• Aid in PCOS diagnosis
• Determination of adrenal or ovarian origin of hyperandrogenism

Venous blood (dry tube)

Morning collection. During the follicular phase in women.

• Hirsutism, severe acne, or androgenic alopecia in women
• PCOS workup

Testostérone • DHEA • 17-OH-progestérone • Cortisol

Major adrenal androgen (in DHEA-S form). Specific marker of adrenal androgenic function, allowing distinction between adrenal and ovarian origin.

• Investigation of hyperandrogenism of adrenal origin
• Diagnosis of virilizing adrenal tumors
• Evaluation of adrenal puberty (adrenarche)

Venous blood (dry tube)

No specific preparation required. DHEA-S is stable throughout the day.

• Female virilization of adrenal origin
• Precocious puberty
• Hirsutism workup

Cortisol • Testostérone • Delta 4 androstènedione • 17-OH-progestérone

Central protein of the complement system, involved in the innate immune response. Its measurement allows evaluation of complement system activity.

• Evaluation of complement system activity
• Diagnosis and monitoring of autoimmune diseases (lupus, glomerulonephritis)
• Detection of congenital complement deficiency

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Systemic lupus erythematosus
• Membranoproliferative glomerulonephritis
• Recurrent bacterial infections

C4 • AAN • Anti-ADN • CRP • Immunoglobulines

Quantitative measurement of the three main classes of serum immunoglobulins (IgA, IgG, IgM). Allows assessment of humoral immunity and detection of gammopathies.

• Diagnosis of humoral immune deficiencies
• Detection of monoclonal gammopathy
• Monitoring of myelomas and lymphoproliferative diseases

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Recurrent infections (pneumonia, sinusitis)
• Suspected multiple myeloma
• Celiac disease workup (IgA deficiency)
• Post-bone marrow transplant surveillance

Électrophorèse des protéines • Immuno-fixation • Complément C3 • CRP

Measurement of total immunoglobulin E, involved in type I allergic reactions (immediate hypersensitivity) and antiparasitic defense.

• Assessment of atopic predisposition
• Orientation toward allergic origin of symptoms
• Investigation of parasitic infection

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Asthma, allergic rhinitis, or atopic eczema
• Chronic urticaria
• Blood hypereosinophilia

IgE spécifiques • FNS • Prick tests

Measurement of total prostate-specific antigen and its free fraction. Primary marker used in prostate cancer screening and monitoring.

• Prostate cancer screening
• Post-treatment prostate cancer monitoring
• Benign prostatic hyperplasia surveillance

Venous blood (dry tube)

No digital rectal examination or sexual intercourse within 48 hours before collection. Avoid intense exercise (cycling).

• Screening in men over 50 years old
• Post-prostatectomy follow-up
• Elevated PSA with low free/total ratio

Toucher rectal • Biopsie prostatique • IRM prostatique

Measurement of carcinoembryonic antigen (CEA), an oncofetal glycoprotein. Primarily used in therapeutic monitoring of colorectal cancer.

• Therapeutic monitoring of colorectal cancer
• Early detection of post-surgical recurrence
• Aid in monitoring other cancers

Venous blood (dry tube)

Report active smoking (risk of false positives).

• Post-operative colorectal cancer follow-up
• Tumor staging workup
• Chemotherapy surveillance

CA 19-9 • AFP • Bilan hépatique

Measurement of alpha-fetoprotein, a marker for hepatocellular carcinoma and germ cell tumors. Also used in prenatal screening.

• Screening and monitoring of hepatocellular carcinoma
• Diagnosis and monitoring of germ cell tumors
• Prenatal screening for neural tube defects

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Surveillance of cirrhotic patients (HCC screening)
• Testicular germ cell tumor follow-up
• Second trimester prenatal screening

β-HCG • LDH • Bilan hépatique • Échographie

Tumor marker primarily associated with ovarian cancer. High molecular weight glycoprotein expressed by ovarian epithelial cells.

• Therapeutic monitoring of ovarian cancer
• Detection of post-treatment recurrence
• Aid in diagnosing pelvic mass

Venous blood (dry tube)

Avoid collection during menstruation.

• Ovarian cancer monitoring during chemotherapy
• Adnexal mass on ultrasound
• Severe endometriosis surveillance

CA 15-3 • HE4 • Échographie pelvienne

Tumor marker primarily associated with breast cancer. Used in therapeutic monitoring and detection of breast cancer recurrence.

• Monitoring of metastatic breast cancer
• Detection of recurrence
• Evaluation of treatment response

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Post-operative breast cancer follow-up
• Surveillance under hormone therapy or chemotherapy

ACE • CA 125 • Bilan hépatique • Scintigraphie osseuse

Tumor marker primarily associated with pancreatic and biliary tract cancer. Carbohydrate antigen used in therapeutic monitoring.

• Therapeutic monitoring of pancreatic cancer
• Aid in differential diagnosis of pancreatic masses
• Monitoring of biliary tract cancers

Venous blood (dry tube)

No specific preparation required. Preferably come in the morning.

• Pancreatic mass on imaging
• Post-operative pancreatic cancer follow-up
• Obstructive jaundice of tumoral origin

ACE • AFP • Lipase • Bilirubine • Bilan hépatique

Measurement of blood levels of valproic acid (Depakine®), an antiepileptic drug with a narrow therapeutic margin. Essential for dosage adjustment and prevention of toxic effects.

• Verification of therapeutic range (50-100 µg/mL)
• Detection of underdosing or overdosing
• Dosage adjustment

Venous blood (dry tube)

Collection before the morning dose (trough level).

• Epilepsy treated with valproic acid
• Suspected non-compliance with therapy
• Dosage adjustment

50–100 µg/mL (therapeutic range)

Bilan hépatique • FNS • Ammoniémie

Qualitative multi-drug urine screening (cannabis, opiates, cocaine, amphetamines, benzodiazepines). Used in clinical, occupational, and forensic settings.

• Screening for illicit substance use
• Monitoring of patients on substitution therapy
• Forensic and occupational context

Urine (collection at any time)

No specific preparation required. Supervised collection in forensic context.

• Pre-employment or occupational fitness assessment
• Addiction medicine patient monitoring
• Emergency setting (acute intoxication)

Bilan hépatique • Créatinine • FNS